How to fine-tune molecular structures within vaccines to improve immune responses

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A vaccine's molecular structure plays a key role in determining how the immune system responds and prepares to protect the body from future exposure to a specific pathogen. To develop a vaccine that offers long-term protection from HIV, it's essential to promote a long-lasting immune response in which immune cells and antibodies prepared to combat the virus persist within the body. This has inspired scientists to find ways to alter vaccine structure to increase the duration and persistence of the immune response.