Mitochondrial proteins may trigger inflammation by mimicking bacterial distress signals

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Mitochondria are often called the powerhouses of the cell. But their ancient origins may also make them drivers of inflammation. Researchers at the University of Illinois Chicago have discovered that proteins released from mitochondria can activate the immune system in a similar way to invading bacteria. The findings suggest that remnants of mitochondria's evolutionary past may contribute to inflammation in infections and autoimmune disorders.